Dietary intake of polyunsaturated fatty acids, their food sources and fertility in females and males: a preconception prospective population-based cohort study.

ABSTRACT:

Background

Seafood, nuts, and seeds are key dietary sources of polyunsaturated fatty acids (PUFAs), which may benefit reproductive health.

Objectives

This study aims to investigate associations of periconception dietary intake of PUFA-rich foods and omega-3 and omega-6 PUFAs with fecundability and subfertility in females and males.

Methods

Among 830 females and 651 males, participating in a population-based prospective cohort study from preconception onwards, we assessed periconception dietary intake at median 12.4-wk gestation (95% range: 10.9, 18.4) and time to pregnancy via questionnaires. Fecundability was defined as the probability of conceiving within 1 mo and subfertility as time to pregnancy ≥12 mo or use of assisted reproductive technology. Cox proportional h

SUBMITTER: Schipper MC 

PROVIDER: S-EPMC12226746 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature