Effect of zinc supplementation on diarrhoea in HIV infection: a protocol for systematic review and meta-analysis of controlled clinical trials.

ABSTRACT:

Introduction

Diarrhoea is a common problem in people living with HIV. Some trials have demonstrated the effectiveness of zinc supplementation in the prevention and treatment of diarrhoea; however, several studies employing the effectiveness of zinc supplementation for reducing diarrhoea in HIV infection have reported heterogeneous outcomes, necessitating a systematic review to provide an exhaustive summary of current evidence. This review aims to pool the available evidence on the effectiveness of zinc supplementation on diarrhoea in HIV infection.

Methods and analysis

This systematic review protocol follows the Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols. A systematic literature search will be conducted in Chinese and English databases, inclu

SUBMITTER: Li P 

PROVIDER: S-EPMC12226950 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature