Vascular encasement image defined risk factors independently predict surgical complications in neuroblastoma.

ABSTRACT:

Background

Specific image defined risk factors (IDRF) immediately prior to surgery may be more relevant to paediatric oncology surgeons than pre-neoadjuvant IDRFs at diagnosis. The aim of this study was to determine IDRF subtypes that independently predict postoperative complications.

Methods

We searched the New Zealand Children's Cancer Registry for all cases of neuroblastoma treated at a single paediatric oncology centre between January 2007 and February 2021 and determined the IDRF status on pre-operative imaging at diagnosis and after neoadjuvant therapy. Surgical complications (Clavien-Dindo grade) were correlated with total number of IDRFs (pre- and post-chemotherapy) and three subsets: vascular encasement (VE), invasive (I), and extensive (E).

Results

Of 101 pa

SUBMITTER: Stokes R 

PROVIDER: S-EPMC12227851 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature