Multidimensional RF pulse design using auto-differentiable spin-domain optimization and its application to reduced field-of-view imaging.

ABSTRACT:

Purpose

Develop a general radiofrequency (RF) pulse design algorithm for the design of three-dimensional (3D) spatially selective refocusing pulses and explore their potential applications in reduced field-of-view imaging.

Methods

Spin-domain representation was used to describe the effect of RF pulses and to formulate the optimization problem. The implementation was based on an auto-differentiable simulator. Spatially selective excitation and refocusing pulses for a small regions of interest were designed with consideration of hardware limits and B₀ and B₁ ⁺ inhomogeneities. The designed RF pulses were validated in simulation as well as in vivo experiments in brain and prostate on a 3T scanner.

Results

Pulses of short duration (4.15 ms

SUBMITTER: Yang J 

PROVIDER: S-EPMC12228547 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature