Association between general anesthesia combined with peripheral nerve blocks versus neuraxial anesthesia without nerve blocks for high-risk isolated distal deep venous thrombosis in patients undergoing knee arthroplasty: a historical cohort study.

ABSTRACT:

Purpose

General anesthesia combined with peripheral nerve blocks has become a common anesthesia regimen for knee replacement surgery. Its association with high-risk isolated distal deep venous thrombosis (IDDVT) remains uncertain.

Methods

In this cohort study, we obtained consecutive data from the electronic inpatient records of Shenzhen Second People's Hospital, including adults who underwent knee arthroplasty from 1 September 2019 to 31 August 2021. The primary outcome was the incidence of high-risk IDDVT. We compared the outcomes in patients who received general anesthesia combined with nerve blocks with those in patients who received neuraxial anesthesia without nerve blocks, using a multivariable regression model with inverse probability weighting according to the prope

SUBMITTER: Luo N 

PROVIDER: S-EPMC12228590 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature