Retrospective Study Supports that Pharmacologic Venous Thromboembolism Prophylaxis After Intracerebral Hemorrhage is Safe, Underused.

ABSTRACT:

Background

Patients with spontaneous non-traumatic intracerebral hemorrhage (ICH) have a heightened risk for venous thrombosis (VTE). The Stroke 2022 Guidelines suggest initiating pharmacologic prophylaxis after hemorrhage stabilization, as measured on repeat imaging within the first 24 hours of admission. However, pharmacologic prophylaxis is underutilized and there remain concerns that initiation of pharmacologic prophylaxis could increase hemorrhage size. This study examines the safety of initiating pharmacologic prophylaxis after hemorrhage stabilization.

Methods

This was a retrospective study of patients discharged with nontraumatic spontaneous ICH. The study population was from Providence Medical Centers in Washington, Oregon, and California. Patients, 18 years or olde

SUBMITTER: Carlisle CL 

PROVIDER: S-EPMC12228634 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature