Individual stress reactivity predicts alcohol craving and alcohol consumption in alcohol use disorder in experimental and real-life settings.

ABSTRACT: Stress- and alcohol cues trigger alcohol craving and alcohol consumption in alcohol use disorder (AUD). However, their interactions on a physiological and psychological level and their effects on daily alcohol craving and alcohol use in real-life situations are not understood yet. We conducted a randomized-controlled experimental study to compare the effects of psychosocial stress against physical stress and a control intervention, each followed by an alcohol cue-exposure, on alcohol craving, subjective stress and saliva cortisol levels (main outcomes) in N = 121 individuals with AUD and collected data on daily alcohol use and craving during a 1-year ambulatory assessment phase. We applied linear mixed models to compare the effects of experimental interventions on the main outcomes and the

SUBMITTER: Zaiser J 

PROVIDER: S-EPMC12229504 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature