Advance Consent for participation in Acute Stroke Trials (ACTION): protocol for a feasibility study.

ABSTRACT:

Introduction

Obtaining informed consent for research from patients in medical emergencies remains a challenge, particularly in acute stroke care as treatment must be administered quickly and patients often arrive in the hospital in a state of incapacitation. Adaptations to standard consenting approaches-such as the use of surrogate consent or deferral of consent-have significant limitations. This feasibility study aims to test a new consenting approach in acute stroke care that we call advance consent. Advance consent has the potential to render emergency trial enrolment faster, fairer and more transparent, leading to more generalisable results.

Methods and design

We will conduct a five-part study at The Ottawa Hospital, a quaternary care stroke centre: (1) administering que

SUBMITTER: Udoh U 

PROVIDER: S-EPMC12230221 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature