Biofilm Formation on Endotracheal and Tracheostomy Tubing: A Systematic Review and Meta-Analysis of Culture Data and Sampling Method.

ABSTRACT: Biofilm formation on tracheal tubing is a key risk factor for ventilator-associated pneumonia. Endotracheal tube microbiology has been systematically reviewed, but tracheostomy tube profiles have not. Analysis of the tube-associated microbiome is not standardised, and sampling methods are varied. We compared the reported microbiomes of endotracheal and tracheostomy tubes and examined the impact of sampling by tracheal aspiration or direct culture. We searched PubMed, SCOPUS, and Web of Knowledge for clinical microbiology studies from 2000-2024, extracting tubing type, sampling method, and the most prevalent genera identified. Genera were compared by Spearman's rank correlation and pairwise analyses by Šidák's test. Extraction from 49 studies identified 30 genera. Pseudomonas was the most p

SUBMITTER: Deshmukh-Reeves E 

PROVIDER: S-EPMC12230368 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature