Diffusion along the perivascular space influenced by handedness and language lateralisation.

ABSTRACT: The DTI-ALPS_index (diffusion tensor image analysis along the perivascular space index) has been tested in several diseases, but a limited number of studies are available in healthy normal populations. Given that some of the examined diseases show asymmetric features (e.g. Parkinson's disease, epilepsy) and considering that the DTI-ALPS_index is calculated from white matter regions involved in motor and language functions, our aim was to examine whether the index is influenced by handedness and/or functional language lateralisation. Eighty-two Caucasian adults (35 males; mean age: 26.91 ± 10.17, range: 18-66 years) were included in this retrospective cross-sectional study. Handedness was assessed by the Edinburgh Handedness Inventory, while language lateralisation was d

SUBMITTER: Perlaki G 

PROVIDER: S-EPMC12230666 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature