Ultrasonic Vocalization Acoustics After Recurrent Laryngeal Nerve Injury and Recovery.

ABSTRACT:

Objectives

The lack of well-defined functional acoustic correlates of vocal fold paralysis in animal models creates challenges for translating basic science studies of recurrent laryngeal nerve (RLN) injury to patients with vocal fold paralysis. Capitalizing on natural communicative rodent ultrasonic vocalizations (USVs), this study aimed to (1) investigate the impact of RLN injury on USV acoustics in both acute and chronic stages of RLN injury and (2) to identify USV parameters with the greatest ecological validity specific to RLN injury.

Methods

USVs were recorded over 2 weeks (acute) in 16 animals and over 30 weeks (chronic) in 8 animals using two USV elicitation paradigms (n = 16 non-elicited, spontaneous; n = 8 elicited, sexually paired). USV acoustic characteristics fr

SUBMITTER: Morrison R 

PROVIDER: S-EPMC12230915 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature