Association Between Perioperative Hypotension and Graft Function in Kidney Transplantation.

ABSTRACT:

Introduction

The impact of perioperative hypotension on graft function after kidney transplantation (KT) has not been well-described; however, it may be expected to negatively impact posttransplant outcomes.

Methods

We conducted a retrospective cohort study of adult patients undergoing KT in a multiprovincial renal program from 2006 to 2019. Using multivariable logistic regression, we assessed the association of intraoperative hypotension (IOH; systolic blood pressure (sBP) ≤ 90 mm Hg within the final hour of surgery) and postoperative hypotension (POH; occurring within the first 2 postoperative days) with delayed graft function (DGF). In secondary analyses, we used adjusted logistic regression or Cox proportional hazards models to assess the impact of hypotension on prolong

SUBMITTER: Morrison SA 

PROVIDER: S-EPMC12231030 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature