The Impact of Hydrostatic Pressure on Fractional Flow Reserve in Saphenous Vein Grafts.

ABSTRACT:

Background

The relationship between height differences related to graft anatomy and physiological pressure indices in coronary bypass grafts has not been studied. We sought to study the impact of hydrostatic pressure on fractional flow reserve (FFR) in saphenous vein grafts (SVGs).

Methods

Included were 66 symptomatic patients (76 SVGs) with prior coronary artery bypass grafting who underwent coronary computed tomography angiography (CCTA) preceding invasive coronary angiography with FFR interrogation of ≥ 1 SVGs. The graft course and height excursion were reconstructed based on CCTA images. The impact of hydrostatic pressure on FFR (corrected FFR) was calculated by adding or subtracting 0.077 mmHg to the distal coronary pressure for every millimeter height difference in a s

SUBMITTER: Hoek R 

PROVIDER: S-EPMC12231170 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature