Optimal techniques for obtaining superior liver specimens at endoscopic ultrasound-guided biopsy: a pilot study on pigs.

ABSTRACT:

Background

Endoscopic ultrasound (EUS)-guided liver biopsy has been an effective method for acquiring liver tissue. However, currently, there is no consensus on the technical details of biopsy sampling. This study aimed to optimize the EUS-guided liver biopsy techniques to improve specimen quality.

Methods

EUS-guided liver biopsies were performed in four porcine subjects with four technical aspects: negative pressure suction, number of actuations, two puncture manipulations, and two types of puncture needles. The primary outcomes were total specimen length (TSL) and complete portal tracts (CPTs), the secondary outcomes included longest specimen length (LSL), number of specimen pieces, specimen fragmentation, blood contamination, and bleeding.

Results

Forty-four biopsy

SUBMITTER: Wu Y 

PROVIDER: S-EPMC12231547 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature