Dataset Information
FabG moonlights as an extracellular adhesin mediates cytoadhesion of Streptococcus suis via interaction with plasminogen.
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ABSTRACT:
SUBMITTER: Guo G
PROVIDER: S-EPMC12232145 | biostudies-literature | 2025 Jul
REPOSITORIES: biostudies-literature
Publications
FabG moonlights as an extracellular adhesin mediates cytoadhesion of Streptococcus suis via interaction with plasminogen.
BMC microbiology 20250704 1
Streptococcus suis serotype 2 (SS2) is an important zoonotic bacterial pathogen that can causes meningitis, septicemia, endocarditis, arthritis, pneumonia, and streptococcal toxic shock-like syndrome in pigs and humans. FabG, an essential reductase in the bacteria type II fatty acid synthesis pathway, is present in the extracellular space and binds to many extracellular matrix components of the host. In this study, we investigated the moonlight function of FabG. First, we found that the transcri ...[more]