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Opportunistic Assessment for Parathyroid Adenoma on CT: A Retrospective Cohort Study Evaluating Primary Hyperparathyroidism-Associated Morbidity Over 10 Years of Follow-Up.


ABSTRACT: BACKGROUND. Primary hyperparathyroidism (PHPT) is underdiagnosed. Opportunistic imaging-based parathyroid gland assessment is a proposed strategy for identifying patients at increased risk of undiagnosed PHPT. However, whether this approach is likely to identify individuals with clinically significant disease is unknown. OBJECTIVE. This study's objective was to assess for associations of the presence of an enlarged parathyroid gland on contrast-enhanced CT with clinical outcomes causally related to PHPT. METHODS. This retrospective cohort study included patients 18 years old or older with at least one contrast-enhanced chest or neck CT examination performed from January 2012 to December 2012, at least one noncontrast CT examination covering the chest or neck region wit

SUBMITTER: Bunch PM 

PROVIDER: S-EPMC12232212 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature