An automated photo-isomerisation and kinetics characterisation system for molecular photoswitches.

ABSTRACT: Physical chemistry parameters such as absorbance, photoconversion quantum yield, and thermal half-lives are crucial for the characterisation of new molecular photoswitch systems. In a traditional workflow, these parameters are challenging and time-consuming to measure. In this paper, a high-throughput flow-based photoswitch characterisation platform with a built-in broad-spectrum LED array and thermal back-conversion capabilities is developed with UV-Vis spectroscopic analysis tools to reduce materials consumption, limit laborous workflows, and improve experimental reproducibility. Following the experiments, an in-house developed Python program is used for easy and fast data analysis. The program is designed to be able to analyse different types of photoswitches depending on the molecular

SUBMITTER: Elholm JL 

PROVIDER: S-EPMC12232385 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature