Psoriasis and cardiovascular risk: associated and protective factors.

ABSTRACT:

Background

Psoriasis is an inflammatory skin disease associated with Metabolic Syndrome (MetS), Steatotic Liver Disease (SLD) and cardiovascular risk. However, the effect of anti-inflammatory therapy on cardiovascular risk is uncertain.

Objectives

To determine the relationship between anti-inflammatory therapy and subclinical atherosclerosis in individuals with psoriasis, using the gold standard carotid-femoral Pulse Wave Velocity (cf-PWV) measurement. Additionally, to evaluate the association between cf-PWV, steatosis and Advanced Fibrosis (AF) using Transient Elastography (TE) by Fibroscan®.

Methods

Cross-sectional study including psoriasis patients submitted to cf-PWV and TE. Steatosis was defined as a controlled attenuation parameter ≥ 275 dB/m, AF as liver stiffn

SUBMITTER: Agoglia L 

PROVIDER: S-EPMC12234172 | biostudies-literature | 2025 May-Jun

REPOSITORIES: biostudies-literature