Financial Feasibility of Developing Sustained-Release Incrementally Modified Drugs in Thailand's Pharmaceutical Industry: Mixed Methods Study.

ABSTRACT:

Background

Thailand's pharmaceutical industry is prioritizing innovation and self-reliance through the development of incrementally modified drugs (IMDs), particularly sustained-release dosage forms. However, the financial feasibility of IMD development remains underexplored.

Objective

This study evaluates the financial feasibility of developing sustained-release IMDs in Thailand, focusing on costs, timelines, and investment requirements to inform strategic decision-making.

Methods

A mixed methods approach was used, combining literature reviews, expert interviews, and financial modeling. Two scenarios were analyzed: (1) only development (phase I) and (2) full clinical trials (phase I to III). Sensitivity analysis was used to assess the impact of key variables on finan

SUBMITTER: Laichapis M 

PROVIDER: S-EPMC12236265 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature