Timeframe for Conversion to Psychosis From Individuals at Clinical High-Risk: A Quantile Regression.

ABSTRACT:

Background and hypothesis

The time taken for an individual who is at the clinical high-risk (CHR) stage to transition to full-blown psychosis may vary from months to years. This temporal aspect, known as the timeframe for conversion to psychosis (TCP), is a crucial but relatively underexplored dimension of psychosis development.

Study design

The sample consisted of 145 individuals with CHR who completed a 5-year follow-up with a confirmed transition to psychosis within this period. Clinical variables along with functional variables such as the Global Assessment of Function (GAF) score at baseline (GAF baseline) and GAF-drop from the highest score in the past year. The TCP was defined as the duration from CHR identification to psychosis conversion. Participants were categoriz

SUBMITTER: Zhang T 

PROVIDER: S-EPMC12236329 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature