Interrelations of aortic spring function, cardiovascular disease risk factors, and left ventricular diastolic function: The Framingham Heart Study.

ABSTRACT:

Background

Energy associated with proximal aortic stretch during systole is recovered as diastolic elastic recoil of the aorta that facilitates left ventricular filling. Impairment of this aortic spring mechanism may contribute to left ventricular diastolic dysfunction. However, cross-sectional and longitudinal inter-relations of cardiovascular disease risk factors, aortic stretch, and left ventricular diastolic function have not been examined. The goal of this study was to assess the cross-sectional and longitudinal associations of cardiovascular disease risk factors and systolic atrioventricular plane displacement (AVPD), a surrogate measure of stretch of the mechanically coupled ascending aorta, with measures of left ventricular diastolic function.

Methods

At two examinat

SUBMITTER: Cooper LL 

PROVIDER: S-EPMC12236873 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature