Global trends in polycystic ovarian syndrome over 30 years: an age-period-cohort study of 204 countries and territories (1990-2021).

ABSTRACT:

Purpose

To characterize global temporal trends in the incidence of polycystic ovary syndrome (PCOS) from 1990 to 2021 by applying an age-period-cohort (APC) analytical framework across 204 countries and territories, and to assess how these incidence patterns vary according to socio-demographic context.

Methods

This study analyzed PCOS incidence trends from 1990 to 2021 across 204 countries using an APC analysis. Data were sourced from the Global Burden of Disease Study 2021, focusing on crude and age-standardized incidence rates, disaggregated by region and socio-demographic index (SDI).

Results

The global incidence of PCOS increased from 1.48 million cases in 1990 to 2.3 million in 2021. The age-standardized incidence rate in 2021 was 63.26 per 100,000 population (95

SUBMITTER: Lin L 

PROVIDER: S-EPMC12239280 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature