Transient colonization with Blastocystis spp. after transmission via fecal microbiota transplantation.

ABSTRACT:

Background

The pathogenicity of Blastocystis spp. is still debated. Guidelines for feces donor screening differ in their advice to screen for Blastocystis spp., but when tested, its presence is a common reason for exclusion. Blastocystis spp. are correlated to increased bacterial alpha-diversity and distinct bacterial groups and therefore its presence may indicate favorable efficacy of fecal microbiota transplantation (FMT). The latest European consensus report no longer advices rejecting feces donors testing positive for Blastocystis spp. Only one paper has been published on human transmission of Blastocystis spp. via frozen FMT.

Objective

To investigate the transmission and long-term effects of Blastocystis-positive FMT, prepared with fresh (i.e., unfrozen) feces.

Metho

SUBMITTER: Benard MV 

PROVIDER: S-EPMC12241144 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature