The effects of sex and age on movie-watching functional connectivity and movie clip classification.

ABSTRACT: Functional connectivity (FC) is a key tool for understanding the complex interactions within the human brain, highlighting connections between various regions. This study delves into the multifaceted influences shaping functional magnetic resonance imaging FC patterns during movie watching, focusing on the effects of sex, age, and movie clip. Leveraging the Human Connectome Project dataset, we systematically examine FC patterns elicited during movie watching. Notably, sex-specific variations in FC are observed, with females exhibiting heightened FC within visual, limbic, and default mode networks, while males display predominant intra-network connectivity within somatomotor and attention networks. Age-related variations further manifest, revealing FC increases with age in early adulthood (

SUBMITTER: Yang C 

PROVIDER: S-EPMC12241178 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature