Evaluation of dried blood spot sampling for verification of exposure to chemical threat agents.

ABSTRACT:

Purpose

Exposure to chemical threat agents (CTAs), including nerve agents, the vesicating agent sulfur mustard, and opioids, remains a significant threat to warfighter and civilian populations. Definitive analytical methods to verify exposure to CTAs require shipping refrigerated or frozen biomedical samples to reference laboratories for analysis. Logistical and financial burdens arise as the transport of biomedical samples is subject to strict restrictions and complex packaging, which, if done incorrectly, can lead to sample deterioration. The use of dried blood spot (DBS) sampling could provide operational improvements for collecting, storing, and shipping important forensic samples. Therefore, this effort focuses on developing DBS techniques with Mitra® 30-µL volumetric absorpti

SUBMITTER: Walker KA 

PROVIDER: S-EPMC12241275 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature