Outcomes of extremely preterm infants exposed to prolonged prelabor rupture of membranes before 24 weeks of gestation.

ABSTRACT:

Background

Preterm prelabor rupture of membranes before or around the limit of fetal viability is associated with serious maternal and neonatal complications, including chorioamnionitis, extremely preterm birth, and pulmonary hypoplasia.

Objective

This study aimed to describe the contemporary outcomes of extremely preterm infants born after prolonged periviable preterm prelabor rupture of membranes and to identify perinatal factors associated with survival and survival without severe neurodevelopmental impairment.

Study design

Among actively treated infants born alive at <27 weeks' gestational age in centers of the Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network from 2012 to 2018, the outcomes of survival and s

SUBMITTER: Younge NE 

PROVIDER: S-EPMC12241454 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature