Assessing Treatment Outcomes in Achalasia Using 4-Dimensional High-resolution Impedance Manometry.

ABSTRACT:

Background/aims

Assessment of treatment response of achalasia often involves multiple procedures. We aim to investigate innovative metrics based on 4-dimensional high-resolution impedance manometry (4D HRM) to assess treatment response in achalasia patients.

Methods

Patients with achalasia treated by pneumatic dilation or myotomy who underwent follow-up evaluations were included. All patients completed high-resolution impedance manometry before and after treatment. 4D HRM analysis based on developed python program measured clearance ratio, intrabolus pressure (IBP), maximum esophagogastric junction diameter, and distensibility index. Good treatment outcomes were defined as barium column height of < 5 cm at 5 minutes on timed barium esophagram (TBE) and Eckardt score ≤ 3.

SUBMITTER: Li M 

PROVIDER: S-EPMC12241924 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature