Accelerating Saturate, Aromatic, Resin, Asphaltene (SARA) Analysis for High-Fidelity Petroleum Profiling via μSARA-HPLC.

ABSTRACT: Saturates, aromatics, resins, and asphaltenes (SARA) analysis is essential for petroleum characterization, providing critical insights into crude oil properties that impact exploration, production, refining, and transport. However, many current methods have issues such as long runtime, system complexity, and reproducibility challenges. To address these issues, this study introduces μSARA-HPLC, an optimized, automated SARA analysis system using high-performance liquid chromatography (HPLC) with fraction collection. The system features three columns: a Polaris Si-SA MetaGuard column for asphaltene precipitation, a ZORBAX SB-CN column for resin separation, and a ZORBAX RX-SIL column for aromatics. The solvent gradients are carefully controlled, with mid-run flow reversal to ensure comprehensi

SUBMITTER: Atwah I 

PROVIDER: S-EPMC12242619 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature