Particle-Driven Synergistic Antibacterial Effect of Silver-Chitosan Nanocomposites Against , , and.

ABSTRACT: Healthcare-associated infections are often challenging to treat as bacteria can rapidly adapt to conventional antibiotics. Therefore, alternative efficient antibacterials are needed. We hypothesized that combining nanosilver with chitosan would yield synergistically acting nanocomposites that could be used in topical treatments (e.g., wound dressings) and surface coatings, whereas the higher the share of chitosan, the higher the synergistic potency. To prove that, three silver-chitosan nanocomposites (nAgCSs) with different Ag-to-chitosan weight ratios (1:0.3, 1:1, and 1:3) were synthesized, physicochemically characterized and evaluated for their antibacterial potency toward clinically critical Gram-negative bacteria and , and Gram-positive bacteria . Experiments were conducted in deionize

SUBMITTER: Laanoja J 

PROVIDER: S-EPMC12242648 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature