Analysis of Poly-3-Hydroxybutyrate Production with Different Microorganisms Using the Dynamic Simulations for Evaluation of Economic Potential Approach.

ABSTRACT: Concerns with sustainability have led to increasing interest in bioprocesses in the last decades. In particular, environmental problems with plastic disposal have been a major issue. Bioplastics such as poly-3-hydroxybutyrate (PHB) are potential substitutes since they are biodegradable and less toxic. However, their production costs are high and optimization is required. Many works have therefore aimed to build strains capable of higher product yields. But in the case of products that share a precursor with biomass and in the case of intracellular metabolites, a trade-off may occur. Not only yield but also final biomass, titer, and productivity have to be considered. Therefore, this work presents an approach named Dynamic Simulations for Evaluation of Economic Potential (DySEEP), which use

SUBMITTER: de Oliveira Santos W 

PROVIDER: S-EPMC12242656 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature