Integrative glycomic analysis reveals the crucial role of protein glycosylation in fungal pathogenesis.

ABSTRACT: Protein glycosylation, a co- and post-translational modification that enhances the functional diversity of the proteome, contributes to various molecular and cellular functions by transferring different polysaccharides onto proteins. During the last decade, the role of glycosylation in plant pathogenic fungi has received significant attention, and glycoproteins are expected to play essential roles in various biological processes including pathogenicity. However, the comprehensive functional genetic analyses for protein glycosylation pathways and glycan structures of phytopathogenic fungi are still largely unknown. Here, we investigated the role of protein glycosylation in Fusarium graminearum by identifying 65 putative genes involved in protein glycosylation and characterizing their functi

SUBMITTER: Moon H 

PROVIDER: S-EPMC12244721 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature