Inter-network Effective Connectivity During An Emotional Working Memory Task in Two Independent Samples of Young Adults.

ABSTRACT:

Background

Effective connectivity (EC) analysis provides valuable insights into the directionality of neural interactions, which are crucial for understanding the mechanisms underlying cognitive and emotional regulation in depressive and anxiety disorders. In this study, we examined EC within key neural networks during working memory (WM) and emotional regulation (ER) tasks in young adults, both healthy individuals and those seeking help from mental health professionals for emotional distress.

Methods

Dynamic causal modeling was used to analyze EC in 2 independent samples (n = 97 and n = 94). Participants performed an emotional n-back task to assess EC across the central executive network (CEN), default mode network (DMN), salience network (SN), and face processing network.

SUBMITTER: Rozovsky R 

PROVIDER: S-EPMC12246172 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature