Acute session of three endurance exercise intensities alters subcutaneous adipose tissue transcriptome in regular exercisers.

ABSTRACT: The primary aim of this study was to compare the acute effects of three exercise intensities on abdominal subcutaneous adipose tissue (aSAT) transcriptome in regular exercisers. A total of 45 adults who exercise regularly were assigned to perform a single session of either low-intensity continuous (LOW; 60min at 30% VO₂max; n=15), moderate-intensity continuous (MOD; 45min at 65% VO₂max; n=15), or high-intensity interval exercise (HIGH; 10×1min at 90% VO₂max interspersed with 1min active recovery; n=15). aSAT biopsy samples were collected before and 1.5hours after the exercise session for bulk RNA sequencing and targeted protein immunoassays. HIGH upregulated genes involved in cytokine secretion, insulin signaling, and proteolysis while MOD and LOW upregulat

SUBMITTER: Ahn C 

PROVIDER: S-EPMC12247987 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature