Chromosome-Contiguous Reference Genome for <i>Spirometra</i> to Underpin Future Discovery Research.

ABSTRACT: Sparganosis is a neglected food- and water-borne zoonotic disease caused by members of the tapeworm genus Spirometra. More than 1600 human cases have been reported in the literature, primarily in Korea and China; however, the clinical significance of sparganosis is likely underestimated. The control of this disease is challenging in endemic regions because of the complexity of its lifecycle and the involvement of many animal host species, and treatment of clinical disease in humans and animals with selected drugs (e.g., mebendazole and/or praziquantel), even at elevated doses, is often ineffective, such that novel interventions are needed. It is anticipated that the use of molecular technologies should allow the identification of new intervention targets in crucial biological proces

SUBMITTER: Young ND 

PROVIDER: S-EPMC12249497 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature