Predecompression and postdecompression cognitive and affective changes in Chiari malformation type I.

ABSTRACT:

Objective

The role of the cerebellum in cognitive function and psychiatric symptoms is poorly understood and particularly understudied in patients with cerebellar pathologies such as Chiari malformation type I (CM-I). Additionally, it is unclear if interventions targeted toward the cerebellum might impact these life-altering symptoms. The authors sought to characterize pre- and postoperative cognitive and psychiatric function in CM-I patients as evidence for targeted cerebellar treatment for some cognitive and psychiatric conditions.

Methods

This prospective study included surgical patients with CM-I who reported cognitive or psychiatric dysfunction. Patients completed a preoperative assessment and a parallel assessment 6 months following surgery. Neuropsychological evaluati

SUBMITTER: Henry LC 

PROVIDER: S-EPMC12256137 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature