Global, regional, and national lifetime risks of developing benign prostatic hyperplasia in men aged over 40: a population-based cross-sectional study from 1990 to 2021.

ABSTRACT:

Background

Benign prostatic hyperplasia (BPH) is a prevalent condition among older men that significantly reduces quality of life. Despite its global impact, comprehensive estimates of lifetime risk remain limited. This study aims to quantify the lifetime risk of BPH at both global and regional levels using data from the Global Burden of Disease (GBD) 2021.

Materials and methods

We estimated the lifetime risk of developing BPH in men aged over 40 using the "adjusted for multiple primaries (AMP)" method, derived from age-specific incidence rates provided by GBD. The analysis included data from 204 countries and regions covering the period from 1990 to 2021, stratified by age, region, and sociodemographic index (SDI).

Results

In 2021, the global lifetime risk of BPH fro

SUBMITTER: Chen Y 

PROVIDER: S-EPMC12257823 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature