Participants' perspectives of the advanced ovarian cancer biomarker study VALTIVE1: a qualitative study.

ABSTRACT:

Objectives

VALTIVE1 is a multi-centre, single-arm, non-interventional biomarker study for patients with advanced ovarian cancer. Plasma samples (Tie2 concentration) are collected to detect vascular control in tumours during standard treatment with chemotherapy and bevacizumab. This qualitative study embedded in VALTIVE1 aimed to assess the acceptability and feasibility of a potential VALTIVE2 trial. It explored the participants' perceptions of the study and treatments and how they might feel if bevacizumab were discontinued based on the results from the biomarker test.

Design

This qualitative study used semi-structured telephone interviews, which were analysed using deductive and inductive thematic analysis.

Settings

Cancer treatment sites in the UK.

Participants</

SUBMITTER: Holland-Hart D 

PROVIDER: S-EPMC12258328 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature