Affordable plasmonic biosensing: democratizing SERS with scalable, field-compatible substrate fabrication.

ABSTRACT: Efficient and accurate plasmonic biosensing in the field remains a significant challenge. Despite its potential to revolutionize point-of-care (PoC) diagnostics through its unparalleled sensitivity and precise molecular fingerprinting capabilities, adoption of traditional surface-enhanced Raman spectroscopy (SERS) in the field has not proven feasible yet. High production and material costs, complex fabrication methods, reliance on specialized equipment, and persistent issues with sensor stability and reproducibility continue to impede development for PoC use. Addressing these challenges, this study innovates a democratized and cost-effective fabrication kit that enables the production of SERS substrates using commonly available materials and straightforward electrochemistry techniques with

SUBMITTER: Arora S 

PROVIDER: S-EPMC12258937 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature