Association Between Prenatal Antibiotic Exposure and Infant Wheeze Outcomes.

ABSTRACT:

Aim

This study examined the association between antibiotic exposure during pregnancy and the development of wheezing and cough during infancy.

Methods

We analysed data from 12 cohorts in the Environmental influences on Child Health Outcomes Cohort Consortium. Outcomes during the first 18 months after birth included the presence of wheeze or dry cough and treatment or intervention for these symptoms, including medications, emergency room visits, and hospitalisations. We used generalised estimating equations and logistic models with adjustment for inverse propensity scores for exposure to antibiotics.

Results

A total of 4721 pregnancies were included, resulting in 4779 infants. Overall, 1,701/4,721 (36%) individuals received antibiotics during pregnancy, and wheezing wa

SUBMITTER: Greenberg RG 

PROVIDER: S-EPMC12259374 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature