Cognitive impairment and dementia in Latin American individuals with parkinsonism and Parkinson's disease: A 10/66 Dementia Research Group study.

ABSTRACT:

Introduction

This study aimed to determine the associations between parkinsonism and Parkinson's disease (PD) with cognitive impairment and dementia in a multi-country cohort in Latin America, using data from the 10/66 Dementia Research Group.

Methods

This population-based prospective cohort study was conducted in six Latin American countries, including 11,321 participants 65 years of age or older living in urban and rural areas.

Results

At baseline, the prevalence of cognitive impairment in people with parkinsonism and PD was 33% and 26%, respectively. Parkinsonism (odds ratio [OR] 2.2 [95% confidence interval [CI] 1.9-2.6] and PD (OR 1.9 [95% CI 1.4-2.4]) were individually associated with baseline cognitive impairment and incident dementia. The pooled sub-hazard rat

SUBMITTER: Khan N 

PROVIDER: S-EPMC12260215 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature