Baveno VI-SSM stratifies the risk of portal hypertension-related events in patients with HBV-related cirrhosis.

ABSTRACT:

Background/aims

Cirrhotic patients with liver stiffness measurement (LSM) <20 kPa and platelet count ≥150×109/L (Baveno VI criteria), otherwise spleen stiffness measurement (SSM) ≤40 kPa (Baveno VI-SSM criteria) can avoid endoscopy screening; however, no prospective data for their hepatic outcomes.

Methods

Compensated cirrhosis with HBV were prospectively enrolled from April 2019 to April 2022 and followed until July 2023. All patients underwent LSM, SSM and esophagogastroduodenoscopy assessment.

Results

Among 1,224 patients enrolled with median follow-up of 30 months (interquartile range, 21-42), the incidence of decompensation was greater in 560 patients with unfavored Baveno VI criteria (0.5 vs. 20.4 per 1,000 person-years, P=0.0004) than that in 664 patients with

SUBMITTER: Wang H 

PROVIDER: S-EPMC12260633 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature