Trends in Sudden Cardiac Death Related Mortality in Adults in the United States: A CDC WONDER Database Analysis, 1999-2020.

ABSTRACT:

Background

Sudden cardiac death (SCD) is a leading cause of mortality in the United States, with significant variations across demographic and geographic factors. This study analyzes trends in SCD-related mortality among adults (> 25 years) from 1999 to 2020 using the CDC WONDER database.

Methods

We extracted data on SCD-related deaths (ICD-10 code I46.1) and calculated age-adjusted mortality rates (AAMR) per 100 000 population, stratified by sex, race/ethnicity, urbanization, and census region. Joinpoint regression was performed to estimate the annual percent change (APC) and average annual percent change (AAPC) with 95% confidence intervals (CI).

Results

A total of 279 599 SCD-related deaths were recorded from 1999 to 2020. Overall AAMR declined significantly (AAPC:

SUBMITTER: Bhagwan R 

PROVIDER: S-EPMC12261031 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature