Endoscopic Features of Gastrointestinal Amyloidosis: A Proposed Endoscopic Classification.

ABSTRACT:

Background/aims

Gastrointestinal amyloidosis (GIA) is a common condition that presents with a variety of endoscopic features. However, the classification of these endoscopic features of GIA and its clinical implications have not been investigated.

Methods

The endoscopic findings of 127 patients with GIA were reviewed and classified by three experienced endoscopists. The relationships of the endoscopic classification of GIA with clinical amyloidosis entities, symptoms, and patient outcomes were evaluated.

Results

Five distinct types of endoscopic lesion features were identified in GIA patients: protruding, granular, hemorrhagic, ulcerative, and nonspecific. The hemorrhagic type was most common (n=32, 25.2%), followed the by protruding (n=30, 23.6%), ulcerative (n=28, 2

SUBMITTER: Song JH 

PROVIDER: S-EPMC12261126 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature