A metal-organic framework with chiral nanochannels for enantioselective fluorescence switching of amino alcohols.

ABSTRACT: The origin of chirality in metal-organic frameworks (MOFs) from achiral linkers remains largely unpredictable, as it mainly stems from the intrinsic arrangement of structural components within the framework. To date, only a handful of reports have explored the achiral ligands for chiral MOF synthesis; their potential for chiral molecular recognition remains a fascinating area of research. Here, we have synthesised a 3-D Co-bpy MOF with chiral nanopores using an achiral linker, which undergoes spontaneous chirality induction through asymmetric crystallization. The MOF crystallizes in a P4₁2₁2 chiral space group, featuring distinctive 4-fold helical chains generating chiral nanochannels along the c-axis. Remarkably, this structural arrangement enables Co-b

SUBMITTER: Ladhi R 

PROVIDER: S-EPMC12261334 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature