Effect of <i>Bifidobacterium longum</i> subsp. <i>infantis</i> YLGB-1496 on common diseases in pediatrics: a randomized, blinded, placebo-controlled trial.

ABSTRACT:

Introduction

Respiratory, gastrointestinal, and allergic diseases can significantly impact both the physical and mental health of children, affecting their overall quality of life. This study aimed to evaluate the preventive effects and safety of Bifidobacterium longum subsp. infantis YLGB-1496 in relation to respiratory, gastrointestinal, and allergic diseases in children.

Methods

Eligible healthy children were randomly assigned to either an intervention group (IG, n = 50), which received the probiotic, or a control group (CG, n = 50), which received a placebo, for a duration of 3 months. The primary outcome was the morbidity of upper respiratory tract infections (URTIs). Gut microbiota profiles were assessed via fecal 16S rRNA sequencing. Fecal

SUBMITTER: Zhang X 

PROVIDER: S-EPMC12261461 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature