MRI-based texture analysis for the evaluation of the response to neoadjuvant chemoimmunotherapy in locally advanced head and neck squamous cell carcinoma.

ABSTRACT:

Background

Neoadjuvant chemoimmunotherapy (NCIT) has emerged as a promising approach for patients with locally advanced head and neck squamous cell carcinoma (LA-HNSCC). However, the risk of immune-related adverse events (irAEs) should be taken seriously. And subsequent treatment strategies are determined on the basis of the neoadjuvant effect. Therefore, identifying a robust and effective method to recognize sensitive patients and monitor treatment response is highly important. The study investigated the ability of texture analysis of MRI to predict treatment response after NCIT in patients with LA-HNSCC, and compared it with several clinical indicators.

Methods

This retrospective study included 49 LA-HNSCC patients who received NCIT followed by surgery. Texture features we

SUBMITTER: Wei H 

PROVIDER: S-EPMC12261655 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature