Combined Auditory, Tactile, and Visual fMRI Reveals Sensory-Biased and Supramodal Working Memory Regions in Human Frontal Cortex.

ABSTRACT: Selectivity for sensory modality characterizes distinct subregions of the human brain, well beyond the primary sensory cortices. We previously identified frontal and posterior cortical regions that are preferentially recruited for visual vs. auditory attention and working memory (WM). Here, we extend our approach to include tactile cognition and to characterize cortical regions recruited by WM in each of three sensory modalities. The joint organization of visual-selective, auditory-selective, tactile-selective, and supramodal WM recruitment within individual subjects has not been fully investigated previously. Male and female human subjects participated in a blocked fMRI task requiring them to perform N-back WM judgements in auditory, visual, or tactile (haptic) modalities. We confi

SUBMITTER: Tobyne SM 

PROVIDER: S-EPMC12262323 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature