Admixture mapping reveals evidence for multiple mitonuclear incompatibilities in swordtail fish hybrids.

ABSTRACT: How barriers to gene flow arise between closely related species is one of the oldest questions in evolutionary biology. Classic models in evolutionary biology predict that negative epistatic interactions between variants in the genomes of diverged lineages, known as hybrid incompatibilities, will reduce viability or fertility in hybrids. The genetic architecture of these interactions and the evolutionary paths through which they arise have profound implications for the efficacy of hybrid incompatibilities as barriers to gene flow between species. While these questions have been studied using theoretical approaches for several decades, only recently has it become possible to genetically map larger numbers of hybrid incompatibilities. Here, we use admixture mapping in natural hybrid populati

SUBMITTER: Robles NV 

PROVIDER: S-EPMC12262648 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature