Characterization of cellular wound resistance in the giant ciliate <i>Stentor coeruleus</i>.

ABSTRACT: Resistance to mechanical stress is essential for cells to prevent wounding and maintain structural integrity. This capability is especially critical for free-living single-celled organisms, which routinely encounter mechanical stress from their natural habitats. We investigated Stentor coeruleus , a single-celled ciliate known for its remarkable wound repair capacity, as a model for studying mechanical wound resistance. While previous work focused on wound repair in Stentor , the structures that enable it to resist wounding remain poorly understood. We characterized how Stentor resisted mechanical stress during transit through a microfluidic constriction. Using high- speed imaging, we tracked the transit dynamics of the cells and linked them to wounding outcomes. Large

SUBMITTER: Paul R 

PROVIDER: S-EPMC12262725 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature