Within-country heterogeneity in patterns of social contact relevant for tuberculosis infection transmission, prevention, and care.

ABSTRACT: Mycobacterium tuberculosis (Mtb) transmission is driven by variable social, environmental, and biological factors, including the number and duration of indoor contacts. Social contact data can provide information on potential transmission patterns, but is underutilised outside the field of mathematical modelling. We explore three contexts where contact data can provide valuable insights: 1) household contact tracing; 2) infection prevention and control measures (IPC); and 3) contamination in cluster randomised trials (CRTs). A social contact survey was conducted in adults aged 18 and older from three communities with comparable population sizes in South Africa: an urban township and peri-urban and rural clinic catchment areas. Participants reported congregate settings visited over 24-hours

SUBMITTER: LeGrand KE 

PROVIDER: S-EPMC12262862 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature